EthA, a Common Activator of Thiocarbamide-Containing Drugs Acting on Different Mycobacterial Targets
نویسندگان
چکیده
منابع مشابه
EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets.
Many of the current antimycobacterial agents require some form of cellular activation unmasking reactive groups, which in turn will bind to their specific targets. Therefore, understanding the mechanisms of activation of current antimycobacterials not only helps to decipher mechanisms of drug resistance but may also facilitate the development of alternative activation strategies or of analogues...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2007
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01063-06